FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\klarα.ro
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General Information
Symbol
Dmel\klarα.ro
Species
D. melanogaster
Name
FlyBase ID
FBal0197595
Feature type
allele
Associated gene
Dmel\klar
Associated Insertion(s)
Carried in Construct
P{ro-klarα}
Key Links
Transgenic product class
cDNA
(Kracklauer et al., 2007)
wild_type
(Kracklauer et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kracklauer et al., 2007)
wild_type
(Kracklauer et al., 2007)
Mutagen
in vitro construct
(Kracklauer et al., 2007)
Progenitor genotype
Carried in construct
P{ro-klarα}
Cytology
Description

The ro enhancer influences expression of an approximately 8.8 kb AscI fragment containing the cDNA for klarα, a KASH-domain containing isoform of klar.

(Kracklauer et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
ro
Encoded product / tool
klar
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      klarα.ro partially rescues klarmarb-CD4

      (Kracklauer et al., 2007)
      Fails to rescue

      klarα.ro fails to rescue klarmarb-CD4

      (Kracklauer et al., 2007)
      Comments

      Most photoreceptor nuclei are positioned appropriately (i.e. apically) in klarmarb-CD4 mutant eye discs that also have a copy of klarα.ro. However, cone cell nuclei remain positioned randomly - many are basal to the photoreceptor nuclei.

      (Kracklauer et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Expresses klarα in photoreceptors R2/5 and R3/4, beginning just posterior to the furrow.

      (Kracklauer et al., 2007)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      klarα.ro
      Name Synonyms
      Secondary FlyBase IDs
        References (1)