FB2026_02 , released June 18, 2026
Allele: Dmel\B4susi-1
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General Information
Symbol
Dmel\B4susi-1
Species
D. melanogaster
Name
FlyBase ID
FBal0198004
Feature type
allele
Associated gene
Dmel\B4
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Wittwer et al., 2005)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q649term.

(Wittwer et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:13,505,850..13,505,850 [-]
Nucleotide change:

C13505850T

Amino acid change:

Q660term | B4-PA; Q660term | B4-PB; Q660term | B4-PC

Reported amino acid change:

Q649term

Comment:

The reported location of the mutation is relative to GB:AF022364, which uses a downstream translation start relative to the FlyBase annotation. Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Wittwer et al., 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Both B4susi-1/B4susi-1 and B4susi-1/B4susi-4 adults are significantly larger than wild-type. B4susi-1/B4susi-1 adults also have increased numbers of ommatidia per eye and B4susi-1/B4susi-4 adults have larger wings than wild-type.

      (Wittwer et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      B4susi-1 is a suppressor of decreased body size | adult stage phenotype of chico1

      (Wittwer et al., 2005)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      B4susi-1 is a suppressor of ommatidium phenotype of chico1

      (Wittwer et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The small body size and reduced numbers of ommatidia seen in chico1 homozygous adults are partially suppressed by B4susi-1/B4susi-1. The eye phenotype is also partially suppressed by B405337/B405337

      (Wittwer et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      B4susi-1
      Susi1
      (Wittwer et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)