FlyBase Allele Report: Dmel\tal[UAS.cGa]

General Information

Symbol

Dmel\tal^UAS.cGa

Species

D. melanogaster

Name

FlyBase ID

FBal0198102

Feature type

allele

Associated gene

tal

Associated Insertion(s)

Carried in Construct

P{UAS-tal.G}

Also Known As

UAS-tal

Key Links

Transgenic product class

cDNA

(Galindo et al., 2007)

wild_type

(Galindo et al., 2007)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Galindo et al., 2007)

wild_type

(Galindo et al., 2007)

Mutagen

in vitro construct

(Galindo et al., 2007)

Progenitor genotype

Carried in construct

P{UAS-tal.G}

Cytology

Description

UASt regulatory sequences drive expression of tal sequences corresponding to the clone LP10384.

(Galindo et al., 2007)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

tal

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^bab1-GAL4-U

(Pueyo and Couso, 2011)

Phenotype Manifest In

cephalopharyngeal skeleton, with Scer\GAL4^Dll-md23

(Galindo et al., 2007)

embryonic head, with Scer\GAL4^Dll-md23

(Galindo et al., 2007)

leg, with Scer\GAL4^bab1-GAL4-U

(Pueyo and Couso, 2011)

leg joint | ectopic, with Scer\GAL4^bab1-GAL4-U

(Pueyo and Couso, 2011)

metatarsus | ectopic, with Scer\GAL4^dpp.blk1

(Galindo et al., 2007)

sex comb | ectopic, with Scer\GAL4^dpp.blk1

(Galindo et al., 2007)

tibia, with Scer\GAL4^dpp.blk1

(Galindo et al., 2007)

Detailed Description

Statement

Reference

Expression of tal^Scer\UAS.cGa under the control of Scer\GAL4^bab1-GAL4-U results in ectopic leg joints.

(Pueyo and Couso, 2011)

Expression of pri^Scer\UAS.fl in the dorsal leg, under the control of Scer\GAL4^dpp.blk1, produces transformation of the distal tibia and fusion to tarsus 1, and ectopic sex combs in tarsi 1 and 2. These phenotypes are compatible with a transformation of tibial identity towards tarsus.

Ectopic expression of pri^Scer\UAS.fl in the embryonic head, under the control of Scer\GAL4^Dll-md23 produces extra sclerotised elements in the cephalopharyngeal skeleton.

Expression of tal^Scer\UAS.cGa in the dorsal leg, under the control of Scer\GAL4^dpp.blk1, produces transformation of the distal tibia and fusion to tarsus 1, and ectopic sex combs in tarsi 1 and 2. These phenotypes are compatible with a transformation of tibial identity towards tarsus.

Ectopic expression of tal^Scer\UAS.cGa in the embryonic head, under the control of Scer\GAL4^Dll-md23 produces extra sclerotised elements in the cephalopharyngeal skeleton.

(Galindo et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Scer\GAL4^bab1-GAL4-U, ovo^svb.UAS, tal^UAS.cGa has visible phenotype

(Pueyo and Couso, 2011)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^bab1-GAL4-U, tal^UAS.cGa has leg phenotype, suppressible by N^l1N-ts1/N[+]

(Pueyo and Couso, 2011)

Scer\GAL4^bab1-GAL4-U, tal^UAS.cGa has leg joint | ectopic phenotype, suppressible by N^l1N-ts1/N[+]

(Pueyo and Couso, 2011)

Scer\GAL4^bab1-GAL4-U, tal^UAS.cGa has leg phenotype, suppressible by +/Df(3R)Delta-BX12

(Pueyo and Couso, 2011)

Scer\GAL4^bab1-GAL4-U, tal^UAS.cGa has leg joint | ectopic phenotype, suppressible by +/Df(3R)Delta-BX12

(Pueyo and Couso, 2011)

Other

Statement

Reference

Scer\GAL4^bab1-GAL4-U, ovo^svb.UAS, tal^UAS.cGa has tarsal segment phenotype

(Pueyo and Couso, 2011)

Scer\GAL4^bab1-GAL4-U, ovo^svb.UAS, tal^UAS.cGa has leg joint phenotype

(Pueyo and Couso, 2011)

Additional Comments

Genetic Interactions

Statement

Reference

The ectopic leg joint phenotype caused by expression of tal^Scer\UAS.cGa under the control of Scer\GAL4^bab1-GAL4-U is suppressed by N^l1N-ts1/+ (at the restrictive temperature) and by Df(3R)Dl-BX12/+.

Co-expression of ovo^svb.Scer\UAS and tal^Scer\UAS.cGa under the control of Scer\GAL4^bab1-GAL4-Uresults in loss of joints in the tarsi.

(Pueyo and Couso, 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

tal^UAS.cGa/Scer\GAL4^Abd-B-LDN rescues tal^pri-3

(Öztürk-Çolak et al., 2016)

Scer\GAL4^tal-KG/tal^UAS.cGa rescues tal^S68

(Galindo et al., 2007)

Comments

Expression of pri^Scer\UAS.fl under the control of Scer\GAL4^pri.KG01680 rescues the pri^S68 phenotypes in the adult and the embryo.

(Galindo et al., 2007)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

pri^Scer\UAS.fl

tal^Scer\UAS.cGa

tal^Scer\UAS.fl

tal^UAS.cGa

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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