FB2026_02 , released June 18, 2026
Allele: Dmel\talpri-3
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General Information
Symbol
Dmel\talpri-3
Species
D. melanogaster
Name
FlyBase ID
FBal0241052
Feature type
allele
Associated gene
tal
Associated Insertion(s)
Carried in Construct
Also Known As
pri3
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Kondo et al., 2007)
Mutagen
FLPase
(Kondo et al., 2007)
Progenitor genotype
P{XP}d06750
(Kondo et al., 2007)
PBac{RB}e03212
(Kondo et al., 2007)
Cytology
Description

Recombination between the two progenitor insertions has resulted in a deletion that removes the entire tal transcription unit.

(Kondo et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:13,812,893..13,814,765 [+]
Comment:

Deletion resulting from FLP-catalyzed recombination using the FRT-containing transposons P{XP}d06750 and PBac{RB}e03212.

(Kondo et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In the tracheal dorsal trunk of stage 16 talpri-3 homozygous embryos, the protrusions of the apical plasma membrane are irregular with occasionally extended flat regions and the envelope is discontinuous when compared to controls.

      The tracheal dorsal trunk of stage 17 talpri-3 homozygous embryos exhibit either misoriented in twisted tracheal tubes (in most cases) or completely disorganized tanedial folds and F-actin bundles, and the breadth of the taenidial folds is highly variable when compared to controls.

      (Öztürk-Çolak et al., 2016)

      talpri-1/talpri-3 embryos show defects in the dorsal branches and transverse connectives of the tracheal system, including a loss of tracheal network integrity and an irregular tube diameter. The dorsal trunk lacks characteristic F-actin structures in the mutant embryos compared to wild type and the F-actin is disorganised.

      (Kondo et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      pri3
      (Dib et al., 2021)
      pri3
      (Öztürk-Çolak et al., 2016, Kondo et al., 2007)
      talpri-3
      Name Synonyms
      Secondary FlyBase IDs
        References (3)