FlyBase Allele Report: Dmel\Elmod[GD6063]

General Information

Symbol

Dmel\Elmod^GD6063

Species

D. melanogaster

Name

FlyBase ID

FBal0198886

Feature type

allele

Associated gene

Dmel\Elmod

Associated Insertion(s)

Carried in Construct

P{GD6063}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD6063}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD6063

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

viable, with Scer\GAL4^tin.CΔ4

(Neely et al., 2010)

Phenotype Manifest In

wing hair | increased number, with Scer\GAL4^en-e16E

(Weber et al., 2012)

Detailed Description

Statement

Reference

Flies expressing CG10068^GD6063 under the control of either one of Scer\GAL4^dpp.blk1 or Scer\GAL4^en-e16E display normal planar cell polarity in the eye and the wing.

Expression of CG10068^GD6063 under the control of Scer\GAL4^en-e16E results in multiple cellular hairs in the wing.

(Weber et al., 2012)

Adults expressing CG10068^GD6063 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

6063

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Dcr-2^UAS.cDa, Elmod^GD6063, Scer\GAL4^hs.2sev has abnormal planar polarity phenotype

(Weber et al., 2012)

Phenotype Manifest In

Other

Statement

Reference

Dcr-2^UAS.cDa, Elmod^GD6063, Scer\GAL4^hs.2sev has ommatidium phenotype

(Weber et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of CG10068^GD6063 and Dcr-2^Scer\UAS.cDa using Scer\GAL4^hs.2sev results in planar cell polarity (PCP)-abnormalities in ommatidia.

(Weber et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v15948

w¹¹¹⁸; P{GD6063}v15948

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

6063

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG10068^GD6063

Elmod^GD6063

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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