FlyBase Allele Report: Dmel\Mpc1[GD3944]

General Information

Symbol

Dmel\Mpc1^GD3944

Species

D. melanogaster

Name

FlyBase ID

FBal0200716

Feature type

allele

Associated gene

Dmel\Mpc1

Associated Insertion(s)

Carried in Construct

P{GD3944}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD3944}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD3944

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal wound healing | larval stage, with Scer\GAL4^repo

(Li et al., 2020)

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

viable, with Scer\GAL4^tin.CΔ4

(Neely et al., 2010)

Phenotype Manifest In

larval multidendritic class IV neuron, with Scer\GAL4^repo

(Li et al., 2020)

Detailed Description

Statement

Reference

Adults expressing Mpc1^GD3944 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

3944

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Mpc1^GD3944, Scer\GAL4^ppl.PP is a suppressor | partially of embryonic/larval fat body phenotype of Nadk1a^NIG.6145R, Scer\GAL4^ppl.PP

(Xu et al., 2021)

Mpc1^GD3944, Scer\GAL4^ppl.PP is a suppressor | partially of mitochondrion | larval stage phenotype of Nadk1a^NIG.6145R, Scer\GAL4^ppl.PP

(Xu et al., 2021)

Mpc1^GD3944, Scer\GAL4^ppl.PP is a suppressor | partially of embryonic/larval fat body phenotype of FASN1^HM05141, Scer\GAL4^ppl.PP

(Xu et al., 2021)

Mpc1^GD3944, Scer\GAL4^ppl.PP is a suppressor | partially of mitochondrion | larval stage phenotype of FASN1^HM05141, Scer\GAL4^ppl.PP

(Xu et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v15858

w¹¹¹⁸; P{GD3944}v15858

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

3944

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG14290^GD3944

Mpc1^GD3944

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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