FlyBase Allele Report: Dmel\rau[GD14083]

General Information

Symbol

Dmel\rau^GD14083

Species

D. melanogaster

Name

FlyBase ID

FBal0206065

Feature type

allele

Associated gene

Dmel\rau

Associated Insertion(s)

Carried in Construct

P{GD14083}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD14083}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD14083

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PU

(Sieglitz et al., 2013)

photoreceptor cell R7 | third instar larval stage, with Scer\GAL4^sev.PU

(Sieglitz et al., 2013)

photoreceptor cell R7 | third instar larval stage, with Scer\GAL4^Tub.PU

(Sieglitz et al., 2013)

Detailed Description

Statement

Reference

Scer\GAL4^GMR.PU-mediated expression of rau^GD14083 generates a rough eye.

R7 photoreceptor cells are frequently lost from eye imaginal discs in which rau^GD14083 is expressed using Scer\GAL4^sev.PU or Scer\GAL4^tub.PU.

(Sieglitz et al., 2013)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

14083

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

rau^GD14083/Scer\GAL4^repo.PL is an enhancer of embryonic/larval optic stalk surface glial cell | third instar larval stage phenotype of Scer\GAL4^repo.PL, sty^UAS.cHa

(Sieglitz et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of rau^GD14083 further impairs the glial cell wrapping phenotype of Scer\GAL4^repo.PL sty^Scer\UAS.cHa mutants.

(Sieglitz et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v23661

w¹¹¹⁸; P{GD14083}v23661/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

14083

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG8965^GD14083

rau^GD14083

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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