Expression of styScer\UAS.cHa driven by Scer\GAL4how-24B significantly reduces the number of boutons per muscle at the neuromuscular junction of third instar larvae, compared to controls.
Expression of styScer\UAS.cHa under the control of Scer\GAL4hs.2sev causes misrotation and disorganization of ommatidia, missing photoreceptors in 5% of ommatidia, and external roughening of the eye.
Expression of styScer\UAS.cHa under the control of Scer\GAL41151 leads to a decrease in the number of founder cells; there are ~7 dorsal founders and ~8 lateral founders per hemisegment in Scer\GAL41151>styScer\UAS.cHa pupae, compared to 17-22 and 20 of these founder types in control pupae. However, there is no comparable change in the number of fusion-competent myoblasts.
When expression is driven by Scer\GAL4hs.2sev or Scer\GAL4elav-C155 the eyes of the resulting flies are small and disorganized. Majority of ommatidia lack one or more outer photoreceptor cells of the R3/R4/R1/R6 type. The R7 is missing in 11+-4% of Scer\GAL4hs.2sev-driven ommatidia and 18+-6% of Scer\GAL4elav-C155-driven ommatidia. R2/R5 and R8 are unaffected. When expression is driven by Scer\GAL4en-e16E, the number of chordotonal organs in the embryo is reduced. When expression is driven by Scer\GAL4BH1, wing veins fail to form, and the size of the wing blade is reduced. This phenotype is similar to that caused by loss of function Egfr or vn mutants. When expression is driven by Scer\GAL4CY2, resulting eggs had a ventralized egg shell and the resulting embryos were also ventralized. This phenotype is similar to that caused by Egfr loss of function mutants.
When expression is driven by Scer\GAL4mat.αTub67C.T:Hsim\VP16 the resulting phenotype resembles that caused by loss of function alleles in Egfr. When expression is driven by Scer\GAL4T155 the egg is ventralized and the dorsal appendages are fused and reduced. When expression is driven by Scer\GAL4dpp.blk1 the L3 vein of the adult wing is truncated. When expression is driven by Scer\GAL4Bx-MS1096 the L2, L3 and L4 veins of the adult wing are truncated. The size of the wing is somewhat reduced.