FlyBase Allele Report: Dmel\Dlic[GD9681]

General Information

Symbol

Dmel\Dlic^GD9681

Species

D. melanogaster

Name

FlyBase ID

FBal0206868

Feature type

allele

Associated gene

Dmel\Dlic

Associated Insertion(s)

Carried in Construct

P{GD9681}

Also Known As

UAS-dlic-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD9681}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD9681

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

some die during pupal stage, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^tin.CΔ4

(Neely et al., 2010)

Phenotype Manifest In

abdominal dorsal multidendritic neuron ddaC | third instar larval stage, with Scer\GAL4^ppk.PG

(Kelliher et al., 2018)

axon | third instar larval stage, with Scer\GAL4^ppk.PG

(Kelliher et al., 2018)

larval ventral nerve cord | third instar larval stage, with Scer\GAL4^ppk.PG

(Kelliher et al., 2018)

postsynaptic Golgi apparatus | ectopic | third instar larval stage, with Scer\GAL4^ppk.PG

(Kelliher et al., 2018)

Detailed Description

Statement

Reference

Adults expressing Dlic^GD9681 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

9681

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

Dlic^GD9681, Khc^Δhinge2, Scer\GAL4^ppk.PG has axon | third instar larval stage phenotype

(Kelliher et al., 2018)

Dlic^GD9681, Khc^Δhinge2, Scer\GAL4^ppk.PG has larval ventral nerve cord | third instar larval stage phenotype

(Kelliher et al., 2018)

Dlic^GD9681, Khc^Δhinge2, Scer\GAL4^ppk.PG has abdominal dorsal multidendritic neuron ddaC | third instar larval stage phenotype

(Kelliher et al., 2018)

Dlic^GD9681, Khc^Δhinge2, Scer\GAL4^ppk.PG has postsynaptic Golgi apparatus | ectopic | third instar larval stage phenotype

(Kelliher et al., 2018)

Dlic^GD9681, Khc^E177K, Scer\GAL4^ppk.PG has axon | third instar larval stage phenotype

(Kelliher et al., 2018)

Dlic^GD9681, Khc^E177K, Scer\GAL4^ppk.PG has larval ventral nerve cord | third instar larval stage phenotype

(Kelliher et al., 2018)

Dlic^GD9681, Khc^E177K, Scer\GAL4^ppk.PG has abdominal dorsal multidendritic neuron ddaC | third instar larval stage phenotype

(Kelliher et al., 2018)

Dlic^GD9681, Khc^E177K, Scer\GAL4^ppk.PG has postsynaptic Golgi apparatus | ectopic | third instar larval stage phenotype

(Kelliher et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v41686

w¹¹¹⁸; P{GD9681}v41686

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

9681

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Dlic2^GD9681

Dlic^GD9681

(Tillery et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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