FlyBase Allele Report: Dmel\Gyc76C[GD48]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Gyc76C^GD48

General Information

Symbol

Dmel\Gyc76C^GD48

Species

D. melanogaster

Name

FlyBase ID

FBal0207242

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

Transgenic product class

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

visible | adult stage, with Scer\GAL4^A9

(Schleede and Blair, 2015)

visible | adult stage, with Scer\GAL4^hh.PU

(Schleede and Blair, 2015)

Phenotype Manifest In

posterior crossvein, with Scer\GAL4^A9

(Schleede and Blair, 2015)

posterior crossvein, with Scer\GAL4^hh.PU

(Schleede and Blair, 2015)

wing blade, with Scer\GAL4^A9

(Schleede and Blair, 2015)

wing blade, with Scer\GAL4^hh.PU

(Schleede and Blair, 2015)

wing vein L5, with Scer\GAL4^hh.PU

(Schleede and Blair, 2015)

Detailed Description

Statement

Reference

Expression of Gyc76C^GD48 RNAi under the control of either the Scer\GAL4^A9 or the Scer\GAL4^hh.PU driver results in partial or complete loss of posterior crossvein in adult wings and a blistering phenotype when the Gyc76C^GD48 expressing (under Scer\GAL4^hh.PU) flies are kept at 28[o]C. Expression under Scer\GAL4^hh.PU also leads to widening of the wing vein L5, which is not observed when the RNAi is expressed using the Scer\GAL4^dpp.3.7XK driver.

(Schleede and Blair, 2015)

External Data

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

48

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, suppressible by cv^EP1349/cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

NOT suppressed by

Statement

Reference

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, non-suppressible by tok^{UAS.cSa.Tag:HA}, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, non-suppressible by cv^EP1349, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, non-suppressible by cv-2^{UAS.Tag:MYC.Tag:V5,Tag:polyHis}, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, non-suppressible by cv-2^EP1103, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, non-suppressible by sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, non-suppressible by cv^EP1349/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, non-suppressible by cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has visible | adult stage phenotype, non-suppressible by cv^EP1349/cv-2^EP1103, Scer\GAL4^A9

(Schleede and Blair, 2015)

Phenotype Manifest In

Suppressed by

Statement

Reference

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, suppressible by cv^EP1349/cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, suppressible by cv^EP1349/cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

NOT suppressed by

Statement

Reference

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, non-suppressible by cv^EP1349, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, non-suppressible by cv^EP1349, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, non-suppressible by cv-2^{UAS.Tag:MYC.Tag:V5,Tag:polyHis}, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, non-suppressible by cv-2^{UAS.Tag:MYC.Tag:V5,Tag:polyHis}, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, non-suppressible by cv-2^EP1103, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, non-suppressible by cv-2^EP1103, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, non-suppressible by sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, non-suppressible by sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, non-suppressible by cv^EP1349/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, non-suppressible by cv^EP1349/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, non-suppressible by cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, non-suppressible by cv-2^EP1103/sog^UAS.Tag:HA, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, non-suppressible by cv^EP1349/cv-2^EP1103, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, non-suppressible by cv^EP1349/cv-2^EP1103, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has wing blade phenotype, non-suppressible by tok^{UAS.cSa.Tag:HA}, Scer\GAL4^A9

(Schleede and Blair, 2015)

Gyc76C^GD48, Scer\GAL4^A9 has posterior crossvein phenotype, non-suppressible by tok^{UAS.cSa.Tag:HA}, Scer\GAL4^A9

(Schleede and Blair, 2015)

Additional Comments

Genetic Interactions

Statement

Reference

The disruption of the posterior crossvein characteristic for flies expressing Gyc76C^GD48 under the control of Scer\GAL4^A9 is not improved by co-expression of any of the following: tok^{Scer\UAS.cSa.T:Ivir\HA1}, cv^EP1349, cv-2^{Scer\UAS.T:Hsap\MYC.T:SV5\V5,T:Zzzz\His6}, cv-2^EP1103, sog^{Scer\UAS.T:Ivir\HA1}, neither by the pairwise combinations of sog^{Scer\UAS.T:Ivir\HA1} and either cv^EP1349 or cv-2^EP1103 but it is rescued by triple co-expression of sog^{Scer\UAS.T:Ivir\HA1}, cv^EP1349 and cv-2^EP1103.

(Schleede and Blair, 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

48

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Gyc76C^GD48

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections