FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\OambGD696
Open Close
General Information
Symbol
Dmel\OambGD696
Species
D. melanogaster
Name
FlyBase ID
FBal0207820
Feature type
allele
Associated gene
Dmel\Oamb
Associated Insertion(s)
Carried in Construct
P{GD696}
Also Known As
UAS-OambRNAi, UAS-OAMB-RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Dickson et al., 2007.7.18)
Mutagen
in vitro construct
(Dickson et al., 2007.7.18)
Progenitor genotype
Carried in construct
P{GD696}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-GD696
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adult females expressing OambGD696 under the control of either Scer\GAL4GMR44E10 or Scer\GAL4GMR47A04 (and using UAS-Dicer2 to enhance RNAi efficiency) lay significantly fewer eggs and take longer to ovulate an egg than controls. The flies also show defects in trimming of posterior follicle cells (with the Scer\GAL4GMR44E10 driver) and produce fewer trimmed eggs.

      (Deady and Sun, 2015)

      Expression of OambGD696 under the control of Scer\GAL4GMR48B04 in starved flies results in a significant short-term olfactory memory defect following training with arabinose, compared to controls.

      (Huetteroth et al., 2015)

      Flies expressing OambGD696 under the control of Scer\GAL40104 show significantly impaired 3 minute memory after olfactory appetitive conditioning with arabinose.

      (Burke et al., 2012)

      Adults expressing OambGD696 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

      (Neely et al., 2010)

      Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in flightless flies.

      (Schnorrer et al., 2010)
      External Data
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 1 )
      Linkouts
      Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      OambGD696
      Name Synonyms
      Secondary FlyBase IDs
        References (16)