FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\qtcGD8202
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General Information
Symbol
Dmel\qtcGD8202
Species
D. melanogaster
Name
FlyBase ID
FBal0210421
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In males expressing qtcGD8202 pan-neuronally, courtship of females is significantly decreased while male courtship is significantly increased, compared to controls.

Expression of qtcGD8202 in the mushroom bodies under the control of Scer\GAL4Mef2.247 abolishes male discrimination in males.

Targeting expression of qtcGD8202 to the most chemosensory peripheral neurons (under the control of Scer\GAL4GH146) does not affect male discrimination.

Expression of qtcGD8202 in various subsets of the peripheral taste neurons known to be involved in the sex pheromone response (under the control of one of Scer\GAL4Gr66a.PD, Scer\GAL4Gr68a.PB, Scer\GAL4Gr32a.3.776, or Scer\GAL4Gr33a-GAL4) results in high levels of sex discrimination in males. No alteration in female mating behavior is detected.

Adults expressing qtcGD8202 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

Depending on the insertion line used, expression under the control of Scer\GAL4Mef2.PR can result in viable flies or adult/pharate lethality.

Expression under the control of Scer\GAL4pnr-MD237 may result in lethality, depending on the insertion line used.

Expression under the control of Scer\GAL4pnr-MD237 results in extra bristles on the notum in 30-40% of the Scer\GAL4pnr-MD237 expression domain.

Expression under the control of Scer\GAL4pnr-MD237 results in a colour difference between the central Scer\GAL4pnr-MD237 expression domain of the notum and the surrounding lateral region in 70-80% of the Scer\GAL4pnr-MD237 expression domain.

Expression under the control of Scer\GAL4pnr-MD237 results in the absence of 20-30% of the Scer\GAL4pnr-MD237-expressing area of the notum.

External Data
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Linkouts
Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
qtcGD8202
Name Synonyms
Secondary FlyBase IDs
    References (7)