FlyBase Allele Report: Dmel\scrib[CA07683]

General Information

Symbol

Dmel\scrib^CA07683

Species

D. melanogaster

Name

FlyBase ID

FBal0211806

Feature type

allele

Associated gene

Dmel\scrib

Associated Insertion(s)

P{PTT-GA}scrib^CA07683

Carried in Construct

Also Known As

CA07683, Scrib-GFP, Scrib:GFP

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Buszczak et al., 2007)

Progenitor genotype

Associated Insertion(s)

P{PTT-GA}scrib^CA07683

Cytology

Description

Insertion within an exon.

(Buszczak et al., 2007)

Allele components

Component

Use(s)

Inserted element

P{PTT-GA}

protein trap

Tagged with

EGFP

green fluorescent protein

Tag:polyHis

epitope tag

purification tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:26,568,062..26,568,062 [+]

(Huang et al., 2023, Gui et al., 2016, Buszczak et al., 2007)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

neoplasia | larval stage, with Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

viable

(Buszczak et al., 2007)

Phenotype Manifest In

wing disc | larval stage, with Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has neoplasia | larval stage phenotype, suppressible by scrib::α-Cat^{LRR.UAS.Tag:MYC}, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has neoplasia | larval stage phenotype, suppressible by kune::α-Cat^UAS.Tag:MYC, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

NOT suppressed by

Statement

Reference

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has neoplasia | larval stage phenotype, non-suppressible by α-Cat^UAS.Tag:MYC, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has neoplasia | larval stage phenotype, non-suppressible by kune^UAS.Tag:MYC, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has neoplasia | larval stage phenotype, non-suppressible by shg^UAS.Tag:MYC, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has neoplasia | larval stage phenotype, non-suppressible by α-Cat::shg^{shg.ΔCyt.UAS.Tag:MYC}, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has wing disc | larval stage phenotype, suppressible by scrib::α-Cat^{LRR.UAS.Tag:MYC}, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has wing disc | larval stage phenotype, suppressible by kune::α-Cat^UAS.Tag:MYC, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

NOT suppressed by

Statement

Reference

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has wing disc | larval stage phenotype, non-suppressible by α-Cat^UAS.Tag:MYC, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has wing disc | larval stage phenotype, non-suppressible by kune^UAS.Tag:MYC, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has wing disc | larval stage phenotype, non-suppressible by shg^UAS.Tag:MYC, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Avic\GFP^RNAi.R.UAS, Scer\GAL4^ptc-559.1, scrib^CA07683 has wing disc | larval stage phenotype, non-suppressible by α-Cat::shg^{shg.ΔCyt.UAS.Tag:MYC}, Scer\GAL4^ptc-559.1

(Huang et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

scrib^CA07683 is rescued by Scer\GAL4^ptc-559.1/scrib^{LRR.UAS.cGa.Tag:MYC}

(Huang et al., 2023)

scrib^CA07683 is rescued by Scer\GAL4^ptc-559.1/scrib^{UAS.cGa.Tag:MYC}

(Huang et al., 2023)

scrib^CA07683 is rescued by Scer\GAL4^ptc-559.1/scrib^{dLRR.UAS.cGa.Tag:MYC}

(Huang et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

94708

w^*; P{PTT-GA}scrib^CA07683

Notes on Origin

Discoverer

Comments

Protein trap line.

(Buszczak et al., 2007)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

scrib^CA07683

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections