FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\dawex32
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General Information
Symbol
Dmel\dawex32
Species
D. melanogaster
Name
FlyBase ID
FBal0212327
Feature type
allele
Associated gene
Dmel\daw
Associated Insertion(s)
P{?GawB}dawex32
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Serpe and O'Connor, 2006)
Progenitor genotype
P{GawB}dawNP4661
(Serpe and O'Connor, 2006)
Associated Insertion(s)
P{?GawB}dawex32
Cytology
Description

Imprecise excision of a P{GawB} insertion in the first intron of the daw gene, resulting in a 1.6kb deletion of daw, including the start codon. Fragments of the transposable element remain.

(Serpe and O'Connor, 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      4% of homozygous third instar larvae show optic lobe and photoreceptor axon targeting defects.

      (Zhu et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      dawex32 has abnormal neuroanatomy phenotype, enhanceable by Actβed80/Actβed80

      (Zhu et al., 2008)
      Other
      Statement
      Reference

      Actβed80, dawex32/daw4 has lethal | larval stage phenotype

      (Zhu et al., 2008)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      dawex32 has embryonic/larval optic lobe phenotype, enhanceable by Actβed80/Actβed80

      (Zhu et al., 2008)

      dawex32 has axon & eye photoreceptor cell phenotype, enhanceable by Actβed80/Actβed80

      (Zhu et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance of the photoreceptor axon targeting phenotype seen in dawex32 homozygous larvae is increased from 4% to 50% if they are also homozygous for Actβed80.

      (Zhu et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      dawex32
      (Wang et al., 2019, Zhu et al., 2008, Serpe and O'Connor, 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)