FlyBase Allele Report: Dmel\Delta[UASp.cJa]

General Information

Symbol

Dmel\Delta^UASp.cJa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Jordan

FlyBase ID

FBal0212456

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

Carried in Construct

P{UASp-Delta.J}

Also Known As

UASp-Dl

Key Links

Transgenic product class

wild_type

(Jordan et al., 2006)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Jordan et al., 2006)

Mutagen

in vitro construct

(Jordan et al., 2006)

Progenitor genotype

Carried in construct

P{UASp-Delta.J}

Cytology

Description

UASp regulatory sequences drive expression of Dl.

(Jordan et al., 2006)

Allele components

Component

Use(s)

Regulatory region(s)

UASp

binary expression system - regulatory region

Encoded product / tool

Delta

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased occurrence of cell division | oogenesis, with Scer\GAL4^{VP16.mat.αTub67C}

(Jordan et al., 2006)

Phenotype Manifest In

egg chamber, with Scer\GAL4^{VP16.mat.αTub67C}

(Jordan et al., 2006)

female germline stem cell | increased number, with Scer\GAL4^nanos.PG

(Ward et al., 2006)

follicle cell, with Scer\GAL4^{VP16.mat.αTub67C}

(Jordan et al., 2006)

germarium cap cell | increased number, with Scer\GAL4^nanos.PG

(Ward et al., 2006)

Detailed Description

Statement

Reference

Expression of Dl^{Scer\UAS.P\T.cJa} under the control of Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} in the germline in early oogenesis results in a dramatic reduction in the number of mitotically dividing cells. The number of stage 6 egg chambers with normal, mitotically dividing follicle cells is reduced to half those in wild-type chambers.

(Jordan et al., 2006)

Expression of Dl^{Scer\UAS.P\T.cJa} under the control of Scer\GAL4^nos.PG in the female germline results in germaria with extra cap cells and additional germ-line stem cells.

(Ward et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Delta^UASp.cJa, Mad¹², Scer\GAL4^nanos.PG has increased cell number phenotype

(Shcherbata et al., 2007)

Phenotype Manifest In

Suppressed by

Statement

Reference

Delta^UASp.cJa, Scer\GAL4^nanos.PG has female germline stem cell | increased number phenotype, suppressible | partially by Dad^UAS.cTa, Scer\GAL4^nanos.PG

(Ward et al., 2006)

Other

Statement

Reference

Delta^UASp.cJa, Mad¹², Scer\GAL4^nanos.PG has female germline stem cell phenotype

(Shcherbata et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Expressing Dl^{Scer\UAS.P\T.cJa} under the control of Scer\GAL4^nos.PG in Mad¹² mutant GSCs during the larval/pupal stages results in an enlargement of the niche at 7 and 14 days after clone induction. No stem cell maintenance defects are observed. The number of Mad¹² mutant GSCs in the enlarged niche increases from 7 days to 14 days.

(Shcherbata et al., 2007)

Coexpression of Dad^Scer\UAS.cTa with Dl^{Scer\UAS.P\T.cJa}, under the control of Scer\GAL4^nos.PG, partially suppresses the additional germ-line stem cell of females that express only Dl^{Scer\UAS.P\T.cJa}.

(Ward et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Delta^UASp.cJa

Dl^{Scer\UAS.P\T.cJa}

Dl^UASp.cJa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Jordan

Secondary FlyBase IDs

References (4)

Report Sections

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