FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Dscam2null-3
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General Information
Symbol
Dmel\Dscam2null-3
Species
D. melanogaster
Name
FlyBase ID
FBal0213050
Feature type
allele
Associated gene
Dmel\Dscam2
Associated Insertion(s)
TI{TI}Dscam2null-3
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
recombination
(Millard et al., 2007, Millard et al., 2007)
I-SceI
(Millard et al., 2007)
FLPase
(Millard et al., 2007)
ends-out gene targeting
(Millard et al., 2007)
Progenitor genotype
Associated Insertion(s)
TI{TI}Dscam2null-3
Cytology
Description

A 1.8kb fragment of Dscam2 (which includes the initiating Met residue of exon 1) has been replaced by a w[+] marker.

(Millard et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dscam2null-3/Dscam2null-3 somatic clones of lamina monopolar neurons L1 and L2 display a perturbed dendritic array with defects in tiling (arbors extend laterally into the correct layer of the incorrect medulla column).

      (Lah et al., 2014)

      Mutant R8 cells in an otherwise wild-type brain form a normal projection pattern in the medulla.

      (Millard et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dscam2null-3
      (Odierna et al., 2020, Lah et al., 2014, Millard et al., 2010, Millard et al., 2007)
      Dscam2null
      (Millard et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)