FB2026_02 , released June 18, 2026
Allele: Dmel\Apc2123
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General Information
Symbol
Dmel\Apc2123
Species
D. melanogaster
Name
FlyBase ID
FBal0213107
Feature type
allele
Associated gene
Dmel\Apc2
Associated Insertion(s)
P{?EP}Apc2123
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Takacs et al., 2008)
Mutagen
Delta2-3 transposase
(Takacs et al., 2008)
Progenitor genotype
P{EP}Apc2G5028
(Takacs et al., 2008)
Associated Insertion(s)
P{?EP}Apc2123
Cytology
Description

Imprecise excision of the P{EP}Apc2G5028 insertion such that only 45 nucleotides of the original insertion remain.

(Takacs et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:24,164,024..24,164,024 [+]
Comment:

45 nucleotides (ATGATGAAATAACATATGTTATTTATTAAATATGTtATTTCATCATGG) remain at the site of the imprecise excision of P{EP}Apc2G5028. There are 5 ATGs in this sequence but none are in frame with the Apc2 start.

Inserted_sequence:

ATGATGAAATAACATATGTTATTTATTAAATATGTTATTTCATCATGG

(Takacs et al., 2008)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Apc2123/Apc2[+] is a suppressor of eye photoreceptor cell phenotype of ApcQ8

      (Takacs et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Apc2123
      (Takacs et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)