FB2026_02 , released June 18, 2026
Allele: Dmel\norpAhs.PW
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General Information
Symbol
Dmel\norpAhs.PW
Species
D. melanogaster
Name
heat shock construct of Wang
FlyBase ID
FBal0213186
Feature type
allele
Associated gene
Dmel\norpA
Associated Insertion(s)
Carried in Construct
P{hs-norpA.W}
Key Links
Transgenic product class
cDNA
(Wang et al., 2008)
wild_type
(Wang et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wang et al., 2008)
wild_type
(Wang et al., 2008)
Mutagen
in vitro construct
(Wang et al., 2008)
Progenitor genotype
Carried in construct
P{hs-norpA.W}
Cytology
Description

An Hsp70 promoter drives expression of the full-length norpA cDNA.

(Wang et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
norpA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      norpAhs.PW rescues norpAP24

      (Wang et al., 2008)
      Comments

      Expression of norpAhs.PW using heat shock in a norpA36 background results in a rescue of the electroretinogram (ERG) response, depending on the level of norpA protein expression. After a 15 minute heat shock, the flies express approximately 3.8% of the normal protein level and show a severe slow termination of the light response. As the duration of the heat shock is increased, the termination of the photoresponse becomes faster, and expression of approximately 20% of the normal protein level restores a wild-type ERG.

      (Wang et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      norpAhs.PW
      Name Synonyms
      heat shock construct of Wang
      Secondary FlyBase IDs
        References (1)