FlyBase Allele Report: Dmel\pths[GD14168]

General Information

Symbol

Dmel\pths^GD14168

Species

D. melanogaster

Name

FlyBase ID

FBal0214360

Feature type

allele

Associated gene

Dmel\pths

Associated Insertion(s)

Carried in Construct

P{GD14168}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dietzl et al., 2007)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dietzl et al., 2007)

Mutagen

in vitro construct

(Dietzl et al., 2007)

Progenitor genotype

Carried in construct

P{GD14168}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dietzl et al., 2007)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD14168

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell migration | embryonic stage, with Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

decreased cell number | embryonic stage, with Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

lethal - all die before end of pupal stage, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

lethal - all die during larval stage, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

some die during pupal stage, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

Phenotype Manifest In

embryonic/larval plasmatocyte | embryonic stage, with Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

germ band, with Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

yolk, with Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Detailed Description

Statement

Reference

Expression under the control of Scer\GAL4^Mef2.PR results in early larval lethality.

(Schnorrer et al., 2010)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

14168

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^srp.Hemo, pths^GD14168 has abnormal cell migration | embryonic stage phenotype, suppressible by Nprl2^GD4298, Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Scer\GAL4^srp.Hemo, pths^GD14168 has abnormal cell migration | embryonic stage phenotype, suppressible by Iml1^GD7476, Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Scer\GAL4^srp.Hemo, pths^GD14168 has abnormal cell migration | embryonic stage phenotype, suppressible by Tsc1^JF01484/Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^srp.Hemo, pths^GD14168 has embryonic/larval plasmatocyte | embryonic stage phenotype, suppressible by Nprl2^GD4298, Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Scer\GAL4^srp.Hemo, pths^GD14168 has embryonic/larval plasmatocyte | embryonic stage phenotype, suppressible by Tsc1^JF01484/Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Scer\GAL4^srp.Hemo, pths^GD14168 has germ band phenotype, suppressible by Tsc1^JF01484/Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Scer\GAL4^srp.Hemo, pths^GD14168 has germ band phenotype, suppressible by Nprl2^GD4298, Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Scer\GAL4^srp.Hemo, pths^GD14168 has embryonic/larval plasmatocyte | embryonic stage phenotype, suppressible by Iml1^GD7476, Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Scer\GAL4^srp.Hemo, pths^GD14168 has germ band phenotype, suppressible by Iml1^GD7476, Scer\GAL4^srp.Hemo

(Emtenani et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

14168

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG9253^GD14168

pths^GD14168

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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