FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmmm\TRPV1E600K.UAS
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General Information
Symbol
Mmmm\TRPV1E600K.UAS
Species
m. unknown
Name
FlyBase ID
FBal0215202
Feature type
allele
Associated gene
Mmmm\TRPV1
Associated Insertion(s)
Carried in Construct
P{UAS-VR1E600K}
Also Known As
UAS-VR1, UAS-VR1E600K, UAS-trpV1
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Marella et al., 2006)
Progenitor genotype
Carried in construct
P{UAS-VR1E600K}
Cytology
Description

UASt regulatory sequences drive expression of VR1(E600K).

(Marella et al., 2006)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
VR1(E600K)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Mmmm\VR1E600K.Scer\UAS under the control of either Scer\GAL4E49 or Scer\GAL4Gr5a.8.5 show robust extension of the rostrum in response to heat delivered by a heated probe brought within a few millimetres of the fly.

      (Gordon and Scott, 2009)

      Flies expressing Mmmm\VR1E600K.Scer\UAS under the control of Scer\GAL4E409 are attracted to 10μM and 100μM capsaicin (wild-type flies are neutral to this compound at these concentrations).

      (Fischler et al., 2007)

      Flies expressing Mmmm\VR1E600K.Scer\UAS under the control of Scer\GAL4Tre.8.5.cCa are attracted to 10μM and 100μM capsaicin, while flies expressing Mmmm\VR1E600K.Scer\UAS under the control of Scer\GAL4Gr66a.3.153 show an avoidance response to 10μM and 100μM capsaicin (wild-type flies are neutral to this compound at these concentrations).

      (Marella et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mmmm\TRPV1E600K.UAS
      Mmmm\VR1E600K.Scer\UAS
      Mmmm\VR1E600K.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (13)