FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4E409
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General Information
Symbol
Scer\GAL4E409
Species
S. cerevisiae
Name
FlyBase ID
FBal0215568
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}E409
Carried in Construct
Also Known As
E409-gal4, E409
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}E409
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        third instar larval stage
        larval central nervous system | restricted
        (Mosher et al., 2015)
        adult stage
        gustatory receptor neuron of labellar taste peg | subset
        (Sánchez-Alcañiz et al., 2018, Fischler et al., 2007)
        gustatory receptor neuron | subset of adult gnathal ganglion
        (Fischler et al., 2007)
        neuron | subset of adult brain
        (Fischler et al., 2007)
        neuron | subset of adult mushroom body
        (Fischler et al., 2007)
        neuron | subset of fan-shaped body
        (Fischler et al., 2007)
        gustatory receptor neuron of the labellum | subset of anterior maxillary sensory center
        (Miyazaki and Ito, 2010)
        carbon dioxide sensitive neuron
        (Lee et al., 2018)
        Additional Information
        Statement
        Reference

        ScerGAL4E409 drives expression in a subset of gustatory receptor neurons of the labellum that project to the anteriormost region of the anterior maxillary sensory center (AMS1).

        (Miyazaki and Ito, 2010)

        ScerGAL4E409 is expressed in the gustatory receptor neurons of the labellar taste pegs of the proboscis which are sensitive to carbon dioxide. Expression of ScerGAL4E409 in the proboscis is distinct from the expression of AvicGFPGr66a.3x.IRES.2x or AvicGFPGr5a.3x.IRES.2x. The projection of the neurons labeled by ScerGAL4E409 in the anterior subesophageal ganglion does not overlap with the projections labeled by AvicGFPGr66a.3x.IRES.2x or AvicGFPGr5a.3x.IRES.2x.

        (Fischler et al., 2007)
         
        Marker for
        carbon dioxide sensitive neuron
        (Lee et al., 2018)
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Silencing of neurons expressing Scer\GAL4E409 results in increased larval floating in a density-based assay for body fat content. Activation of neurons expressing Scer\GAL4E409 results in decreased larval floating in a density-based assay for body fat content.

        (Mosher et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4E409
        Name Synonyms
        Secondary FlyBase IDs
          References (9)