FB2026_03 , released September 17, 2026
Allele: Dmel\Rab6wrt
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General Information
Symbol
Dmel\Rab6wrt
Species
D. melanogaster
Name
FlyBase ID
FBal0215366
Feature type
allele
Associated gene
Dmel\Rab6
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - genetic evidence

    (Coutelis and Ephrussi, 2007)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: R62C.

    (FlyBase, 1992-)

    This allele is a generic representative for the three alleles: Rab6eER1, Rab6eAM4 and Rab6eAS1 which all have the same lesion (Amino acid replacement: R62C). The generation of these alleles is described in FBrf0090844 == Verheyen et al., 1996, Genetics 144(3): 1127--1141 and the lesion is described in FBrf0111465 == Purcell and Artavanis-Tsakonas, 1999, J. Cell Biol. 146(4): 731--740. Rab6wrt is for use when it is not clear which of the three possible alleles is being referenced.

    (FlyBase, 1992-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    2L:12,108,616..12,108,616 [-]
    Nucleotide change:

    C12108616T

    Amino acid change:

    R62C | Rab6-PA; R62C | Rab6-PB

    Reported amino acid change:

    R62C

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

    (FlyBase, 1992-)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Rab6wrt
        rab6wrt
        (Coutelis and Ephrussi, 2007)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)