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General Information
Symbol
Dmel\Gr64aUAS.cJa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Jiao
FlyBase ID
FBal0215609
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of Gr64a coding sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 does not restore the trehalose-response in Df(3L)ΔGr64 mutants.

Expression of Gr64aScer\UAS.cJa in Df(3L)ΔGr64 mutants under the control of Scer\GAL4Gr5a.1 does not restore the behavioural and electrophysiological responses to any of the sugars sucrose, maltose and glucose.

Df(3L)ΔGr64 mutants expressing both Gr64fScer\UAS.cJa and Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 show a behavioural preference for sucrose over fructose that is very similar to that of wild-type flies. The wild-type frequency of action potentials in response to sucrose is also restored in these animals.

Expression of Gr64aScer\UAS.cJa in Df(3L)ΔGr64 mutants under the control of Scer\GAL4Gr5a.1 do not improve their behavioural and electrophysiological responses to glucose.

Co-expression of Gr64aScer\UAS.cJa and Gr64fScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 restores normal preference for glucose over fructose and wild-type frequencies of glucose dependent actin potentials.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Expression of Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.8.5 in Df(3L)Gr64ab flies fully restores the preferences for sucrose, glucose, or maltose over fructose, but not the trehalose response. Consistent with this, the reduction of action potentials in response to glucose, sucrose, and maltose seen in Df(3L)Gr64ab flies is rescued through expression of Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.8.5. However, the reduction of action potentials in response to trehalose is not rescued.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Gr64aScer\UAS.cJa
Gr64aUAS.cJa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Jiao
Secondary FlyBase IDs
    References (2)