FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Gr64aUAS.cJa
Open Close
General Information
Symbol
Dmel\Gr64aUAS.cJa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Jiao
FlyBase ID
FBal0215609
Feature type
allele
Associated gene
Dmel\Gr64a
Associated Insertion(s)
Carried in Construct
P{UAS-Gr64a.J}
Also Known As
UAS-Gr64a
Key Links
Transgenic product class
wild_type
(Jiao et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Jiao et al., 2007)
Mutagen
in vitro construct
(Jiao et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Gr64a.J}
Cytology
Description

UASt regulatory sequences drive expression of Gr64a coding sequences.

(Jiao et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Gr64a
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 does not restore the trehalose-response in Df(3L)ΔGr64 mutants.

      Expression of Gr64aScer\UAS.cJa in Df(3L)ΔGr64 mutants under the control of Scer\GAL4Gr5a.1 does not restore the behavioural and electrophysiological responses to any of the sugars sucrose, maltose and glucose.

      Df(3L)ΔGr64 mutants expressing both Gr64fScer\UAS.cJa and Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 show a behavioural preference for sucrose over fructose that is very similar to that of wild-type flies. The wild-type frequency of action potentials in response to sucrose is also restored in these animals.

      Expression of Gr64aScer\UAS.cJa in Df(3L)ΔGr64 mutants under the control of Scer\GAL4Gr5a.1 do not improve their behavioural and electrophysiological responses to glucose.

      Co-expression of Gr64aScer\UAS.cJa and Gr64fScer\UAS.cJa under the control of Scer\GAL4Gr5a.1 restores normal preference for glucose over fructose and wild-type frequencies of glucose dependent actin potentials.

      (Jiao et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4Gr5a.8.5/Gr64aUAS.cJa partially rescues Df(3L)Gr64ab

      (Jiao et al., 2007)
      Comments

      Expression of Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.8.5 in Df(3L)Gr64ab flies fully restores the preferences for sucrose, glucose, or maltose over fructose, but not the trehalose response. Consistent with this, the reduction of action potentials in response to glucose, sucrose, and maltose seen in Df(3L)Gr64ab flies is rescued through expression of Gr64aScer\UAS.cJa under the control of Scer\GAL4Gr5a.8.5. However, the reduction of action potentials in response to trehalose is not rescued.

      (Jiao et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Gr64aScer\UAS.cJa
      Gr64aUAS.cJa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Jiao
      Secondary FlyBase IDs
        References (3)