FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pzg7.1
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General Information
Symbol
Dmel\pzg7.1
Species
D. melanogaster
Name
FlyBase ID
FBal0215811
Feature type
allele
Associated gene
Dmel\pzg
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Eggert et al., 2004)
Progenitor genotype
P{EP}CG12974EP756
(Eggert et al., 2004)
Caused by aberration
Df(3L)Z4-7.1
Cytology
Description

Imprecise excision of the P{EP}CG12974EP756 insertion, resulting in an 1500bp deletion that removes part of the CG12974 transcription unit. The transcription start site of Z4 is unaffected.

(Eggert et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous larvae remain in the third instar phase for an extensively prolonged time, but eventually pupariate and die in the early pupal stage.

      Homozygous third instar larvae have many aberrant chromosomes in salivary gland preparations, showing a progressive loss of the band/interband structure, with the severity of disintegration of the banded structure increasing with age. The regions of the chromosome that have lost the band/interband organisation have a decompacted and cloudy appearance.

      Z41.3/Z47.1 larvae have aberrant salivary gland chromosomes which have lost the normal band/interband structure and are disorganised, showing an overall decompaction of the chromosomal material.

      (Eggert et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      pzg7.1 is rescued by pzgTag:MYC

      (Eggert et al., 2004)
      Comments

      The lethal phenotype of the Df(3L)Z4-7.1 chromosome is rescued by the P{Z4myc} construct, which contains the complete Z4 gene, but not the complete CG12974 gene, suggesting that the lethality of the Df(3L)Z4-7.1 chromosome is due to an effect on the Z4 gene.

      (Eggert et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Z47.1
      pzg7.1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)