FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\DysGS12472
Open Close
General Information
Symbol
Dmel\DysGS12472
Species
D. melanogaster
Name
FlyBase ID
FBal0216505
Feature type
allele
Associated gene
Dmel\Dys
Associated Insertion(s)
P{GSV1}DysGS12472
Carried in Construct
Also Known As
GS12472
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GSV1}DysGS12472
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GSV1}
    Regulatory region(s)
    UASt
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Statement
        Reference

        Scer\GAL4G14/DysGS12472 is a suppressor | partially of abnormal neurophysiology | dominant phenotype of cv-c1

        (Pilgram et al., 2011)
        Phenotype Manifest In
        Suppressor of
        Statement
        Reference

        Scer\GAL4G14/DysGS12472 is a suppressor | partially of neuromuscular junction phenotype of cv-c1

        (Pilgram et al., 2011)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The increased quantal content (QC) measured at the neuromuscular junction of cv-c1/+ mutants is reduced as a result of expression of DysGS12472 under the control of Scer\GAL4G14.

        (Pilgram et al., 2011)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        DysGS12472/DysE6 is rescued by Scer\GAL4G14/DysGS12472

        (van der Plas et al., 2006)
        Not rescued by

        DysGS12472/DysE6 is not rescued by Scer\GAL4RapGAP1-OK6/DysGS12472

        (van der Plas et al., 2006)
        Rescues

        Scer\GAL4G14/DysGS12472 rescues DysGS12472/DysE6

        (van der Plas et al., 2006)
        Fails to rescue

        Scer\GAL4RapGAP1-OK6/DysGS12472 fails to rescue DysGS12472/DysE6

        (van der Plas et al., 2006)
        Comments

        Postsynaptic expression of DysGS12472 under the control of Scer\GAL4G14 in a heterozygous DysE6/+ background rescues quantal content to wild-type levels. Expression pre-synaptically (under the control of Scer\GAL4OK6) does not rescue quantal content.

        (van der Plas et al., 2006)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        DysGS12472
        GS12472
        (van der Plas et al., 2006)
        detGS12472
        Name Synonyms
        Secondary FlyBase IDs
          References (2)