FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\dawUAS.cGa
Open Close
General Information
Symbol
Dmel\dawUAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Gesualdi
FlyBase ID
FBal0217506
Feature type
allele
Associated gene
Dmel\daw
Associated Insertion(s)
Carried in Construct
P{UAS-daw.G}
Key Links
Transgenic product class
cDNA
(Gesualdi and Haerry, 2007)
wild_type
(Gesualdi and Haerry, 2007)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Gesualdi and Haerry, 2007)
wild_type
(Gesualdi and Haerry, 2007)
Mutagen
in vitro construct
(Gesualdi and Haerry, 2007)
Progenitor genotype
Carried in construct
P{UAS-daw.G}
Cytology
Description

UAS regulatory sequences drive expression of daw coding sequences from the GH14433 coding EST sequence.

(Gesualdi and Haerry, 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
daw
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of one, two, or four copies of dawScer\UAS.cGa, under the control of Scer\GAL4A9 does not significantly increase wing average size.

      (Gesualdi and Haerry, 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4A9/dawUAS.cGa is a suppressor of wing phenotype of SmoxUAS.cGa

      (Gesualdi and Haerry, 2007)

      Scer\GAL4A9/dawUAS.cGa is a suppressor of wing vein phenotype of SmoxUAS.cGa

      (Gesualdi and Haerry, 2007)
      Other
      Statement
      Reference

      MadUAS.cNa, Scer\GAL4A9, dawUAS.cGa has wing phenotype

      (Gesualdi and Haerry, 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of dawScer\UAS.cGa and SmoxScer\UAS.cGa, under the control of Scer\GAL4A9, results in a significant decrease in wing size to 90% compared to females expressing SmoxScer\UAS.cGa alone. In addition, ectopic wing vein formation observed in wings expressing SmoxScer\UAS.cGa is reduced upon co-expression with dawScer\UAS.cGa.

      Co-expression of dawScer\UAS.cGa and MadScer\UAS.cNa, under the control of Scer\GAL4A9, decreases the wing size to 88% without affecting ectopic vein formation. Male wing discs are smaller in size in these double mutants.

      (Gesualdi and Haerry, 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4da.G32/dawUAS.cGa rescues dawaact1

      (Gesualdi and Haerry, 2007)

      Scer\GAL4hs.PB-Ubi/dawUAS.cGa rescues dawaact1

      (Gesualdi and Haerry, 2007)

      Scer\GAL4386Y/dawUAS.cGa rescues dawaact1

      (Gesualdi and Haerry, 2007)

      Scer\GAL4phtm.PO/dawUAS.cGa rescues dawaact1

      (Gesualdi and Haerry, 2007)
      Comments

      dawaact1 mutant animals can be rescued by ubiquitous expression of dawScer\UAS.cGa using Scer\GAL4da.G32 and Scer\GAL4hs.PB-Ubi (to 66% and 56% of wild-type, respectively).

      Expression of dawScer\UAS.cGa using the neurosecretory driver Scer\GAL4386Y rescues the anal pad phenotype of dawaact1 mutants, with approximately 89% of the expected homozygous animals surviving to become fertile adults.

      Expression of dawScer\UAS.cGa using the Scer\GAL4phm.PO driver, to localise expression to the prothoracic portion of the ring gland, results in rescue of lethality of 84% of dawaact1 mutants.

      (Gesualdi and Haerry, 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      dawScer\UAS.cGa
      dawUAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Gesualdi
      Secondary FlyBase IDs
        References (1)