FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SmoxUAS.cGa
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General Information
Symbol
Dmel\SmoxUAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Gesualdi
FlyBase ID
FBal0217502
Feature type
allele
Associated gene
Dmel\Smox
Associated Insertion(s)
Carried in Construct
P{UAS-dSMAD2.G}
Key Links
Transgenic product class
wild_type
(Gesualdi and Haerry, 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Gesualdi and Haerry, 2007)
Mutagen
in vitro construct
(Gesualdi and Haerry, 2007)
Progenitor genotype
Carried in construct
P{UAS-dSMAD2.G}
Cytology
Description

UAS regulatory sequences drive expression of Smox coding sequences.

(Gesualdi and Haerry, 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Smox
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of SmoxScer\UAS.cGa under the control of Scer\GAL4A9 increases the average wing size to 116%. There are no wing pattern defects even when four copies of SmoxScer\UAS.cGa are expressed.

      (Gesualdi and Haerry, 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Suppressed by
      Enhancer of
      Statement
      Reference

      Scer\GAL4A9/SmoxUAS.cGa is an enhancer of wing vein phenotype of baboQ302D.UAS

      (Gesualdi and Haerry, 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of baboQ302D.Scer\UAS and four copies of SmoxScer\UAS.cGa (under the control of Scer\GAL4A9) results in a small increase in ectopic wing vein formation. No additional wing growth is observed.

      Co-expression of myoglianinScer\UAS.cGa with SmoxScer\UAS.cGa, both under the control of Scer\GAL4A9, suppreses the ectopic vein formation of SmoxScer\UAS.cGa overexpression. The size of the wing remains normal.

      Co-expression of ActβCM.Scer\UAS and SmoxScer\UAS.cGa, both under the control of Scer\GAL4A9 results in mild levels of ectopic wing vein formation.

      Co-expression of dawScer\UAS.cGa and SmoxScer\UAS.cGa, under the control of Scer\GAL4A9, results in a significant decrease in wing size to 90% compared to females expressing SmoxScer\UAS.cGa alone. In addition, ectopic wing vein formation observed in wings expressing SmoxScer\UAS.cGa is reduced upon co-expression with dawScer\UAS.cGa.

      (Gesualdi and Haerry, 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      SmoxScer\UAS.cGa
      SmoxUAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Gesualdi
      Secondary FlyBase IDs
        References (1)