FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\oskstop.UASp
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General Information
Symbol
Dmel\oskstop.UASp
Species
D. melanogaster
Name
FlyBase ID
FBal0217948
Feature type
allele
Associated gene
Dmel\osk
Associated Insertion(s)
Carried in Construct
P{UASp-osk-stop}
Key Links
Transgenic product class
stop_gained
(Zimyanin et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
stop_gained
(Zimyanin et al., 2007)
Mutagen
in vitro construct
(Zimyanin et al., 2007)
Progenitor genotype
oskUASp.cZa
(Zimyanin et al., 2007)
Carried in construct
P{UASp-osk-stop}
Cytology
Description

Nucleotide substitution: A860T.

(Zimyanin et al., 2007)

Amino acid replacement: K178term.

(Zimyanin et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
osk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos laid by oskstop.Scer\UAS.P\T; Scer\GAL4mat.αTub67C.T:Hsim\VP16 mothers have a weaker bicaudal phenotype than those from oskScer\UAS.P\T.cZa; Scer\GAL4mat.αTub67C.T:Hsim\VP16 mothers: Only 30 % have an extreme bicaudal phenotype with no denticle belts. The remainder are typically either symmetrically bicaudal or just have head relplaced by a duplicated telson.

      (Zimyanin et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      oskstop.UASp fails to rescue osk9/osk1

      (Zimyanin et al., 2007)
      Comments

      Maternal oskstop.Scer\UAS.P\T + Scer\GAL4mat.αTub67C.T:Hsim\VP16 fails to rescue the posterior group phenotype seen in cuticles of embryos laid by osk9/osk1 mothers.

      (Zimyanin et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      oskstop.Scer\UAS.P\T
      oskstop.UASp
      Name Synonyms
      Secondary FlyBase IDs
        References (2)