FB2026_02 , released June 18, 2026
Allele: Dmel\mir-14UAS.DsRed(Unk)
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General Information
Symbol
Dmel\mir-14UAS.DsRed(Unk)
Species
D. melanogaster
Name
FlyBase ID
FBal0218159
Feature type
allele
Associated gene
Dmel\mir-14
Associated Insertion(s)
Carried in Construct
P{UAS-DsRed-mir-14}
Also Known As
UAS-DSred-miR-14
Key Links
Transgenic product class
wild_type
(Varghese and Cohen, 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Varghese and Cohen, 2007)
Mutagen
in vitro construct
(Varghese and Cohen, 2007)
Progenitor genotype
Carried in construct
P{UAS-DsRed-mir-14}
Cytology
Description

UASt regulatory sequences drive expression of a 500bp genomic fragment containing the mir-14 hairpin. The mir-14 sequence is tagged with DsRed(Unk).

(Varghese and Cohen, 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
mir-14
Tagged with
DsRed(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of mir-14Scer\UAS.T:Disc\RFP under the control of Scer\GAL4Ilp2.215-3 results in adult flies with a reduced total body fat to total body protein ratio compared to controls.

      (Varghese et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4sca.PU/mir-14UAS.DsRed(Unk) is a non-suppressor of visible phenotype of Scer\GAL4sca.PU, miGD11624

      (Szuplewski et al., 2012)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4sca.PU/mir-14UAS.DsRed(Unk) is a non-suppressor of macrochaeta phenotype of Scer\GAL4sca.PU, miGD11624

      (Szuplewski et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      mir-14UAS.DsRed(Unk)/Scer\GAL4arm.PS rescues mir-14Δ1

      (Varghese et al., 2010)

      mir-14UAS.DsRed(Unk)/Scer\GAL4Ilp2.215-3 rescues mir-14Δ1

      (Varghese et al., 2010)
      Fails to rescue

      mir-14UAS.DsRed(Unk)/Scer\GAL4Lsp2.PH fails to rescue mir-14Δ1

      (Varghese et al., 2010)
      Comments

      Expression of mir-14Scer\UAS.T:Disc\RFP under the control of Scer\GAL4Lsp2.PH does not rescue the elevated total body fat to total body protein ratio seen in mir-14Δ1 adults.

      Expression of mir-14Scer\UAS.T:Disc\RFP under the control of either Scer\GAL4Ilp2.215-3 or Scer\GAL4arm.PS rescues the elevated total body fat to total body protein ratio seen in mir-14Δ1 adults.

      (Varghese et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mir-14Scer\UAS.T:Disc\RFP
      mir-14UAS.DsRed(Unk)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)