FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mcm5+t4
Open Close
General Information
Symbol
Dmel\Mcm5+t4
Species
D. melanogaster
Name
FlyBase ID
FBal0218352
Feature type
allele
Associated gene
Dmel\Mcm5
Associated Insertion(s)
Carried in Construct
P{Mcm5+t4}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Lake et al., 2007)
wild_type
(Lake et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Lake et al., 2007)
wild_type
(Lake et al., 2007)
Mutagen
in vitro construct
(Lake et al., 2007)
Progenitor genotype
Carried in construct
P{Mcm5+t4}
Cytology
Description

4kb SacII-XbaI genomic fragment containing the entire Mcm5 gene, plus 809bp of 3' sequences and 578bp of 5' sequences (this includes the 5' UTR and 164bp of coding sequence of the Art1 gene).

(Lake et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
Mcm5
Encoded product / tool
Mcm5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:10,787,950..10,791,983 [+]
Linked to:
SstII-XbaI restriction fragment
(Lake et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Mcm5+t4 rescues Mcm5exc222

      (Lake et al., 2007)

      Mcm5+t4 rescues Mcm5A7

      (Lake et al., 2007)
      Comments

      Mcm5+t4 rescues the lethality of Mcm5exc222 and the meiotic defects of Mcm5A7.

      (Lake et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Mcm5+t4
      Name Synonyms
      Secondary FlyBase IDs
        References (3)