FB2026_03 , released September 17, 2026
Allele: Dmel\Mcm5exc222
Open Close
General Information
Symbol
Dmel\Mcm5exc222
Species
D. melanogaster
Name
FlyBase ID
FBal0218351
Feature type
allele
Associated gene
Dmel\Mcm5
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Lake et al., 2007)
Progenitor genotype
P{SUPor-P}KG05409
(Lake et al., 2007)
Cytology
Description

Imprecise excision of the P{SUPor-P}KG05409 insertion, resulting in a 982bp deletion that removes 332bp upstream of Mcm5 and 650bp of the Mcm5 transcription unit.

(Lake et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:10,788,196..10,789,177 [+]
Comment:

982 bp deletion resulting from the imprecise excision of the P{SUPor-P}KG05409 insertion.

(Lake et al., 2007)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant third instar larvae have a small central nervous system and they lack imaginal discs. The polytene chromosomes of the salivary glands appear normal.

      (Lake et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Mcm5exc222 is rescued by Mcm5+t4

      (Lake et al., 2007)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mcm5exc222
      (Rubio-Ferrera et al., 2022)
      mcm5exc222
      (Lake et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)