FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\decfc106ΔV288-E473
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General Information
Symbol
Dmel\decfc106ΔV288-E473
Species
D. melanogaster
Name
FlyBase ID
FBal0219028
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Carried in construct
Cytology
Description

Internal deletion of sequences encoding amino acid residues V288-E473.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Females carrying dec-1fc106ΔV288-E473 produce only collapsed eggs.

Females carrying dec-1fc106ΔV288-E473 in a wild-type background are sterile.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

dec-1fc106ΔV288-E473 is a dominant female sterile mutation that can be used as an eggshell marker for complete follicle cell clones of a mutation of interest; FRT-mediated recombination in females transheterozygous for a mutation of interest and dec-1fc106ΔV288-E473 can generate egg chambers containing homozygous mutant follicle cells that lack dec-1fc106ΔV288-E473. Eggs derived from egg chambers with large or complete mutant follicle cell clones are readily identifiable because they remain intact, whereas those produced by non-mutant follicular epithelia retaining dec-1fc106ΔV288-E473 collapse.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
dec-1fc106ΔV288-E473
decfc106ΔV288-E473
Name Synonyms
Secondary FlyBase IDs
    References (2)