FlyBase Allele Report: Dmel\G9a[RG5]

General Information

Symbol

Dmel\G9a^RG5

Species

D. melanogaster

Name

FlyBase ID

FBal0219056

Feature type

allele

Associated gene

Dmel\G9a

Associated Insertion(s)

TI{TI}G9a^RG5

Carried in Construct

Also Known As

dG9a^RG5

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Seum et al., 2007)

Mutagen

recombination

(Seum et al., 2007)

ends-out gene targeting

(Seum et al., 2007)

Progenitor genotype

Associated Insertion(s)

TI{TI}G9a^RG5

Cytology

Description

Deletion of the entire G9a open reading frame of G9a. A loxP site is present in place of the deleted sequence.

(Seum et al., 2007)

Allele components

Component

Use(s)

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Seum et al., 2007)

non-suppressor of variegation, with P{hsp26-pt-T}8-M76

(Wang et al., 2014)

non-suppressor of variegation, with P{hsp26-pt-T}39C-66

(Wang et al., 2014)

viable

(Seum et al., 2007)

Phenotype Manifest In

Detailed Description

Statement

Reference

No melanotic masses form in the heads of G9a^RG5 mutant animals.

(Wang et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

G9a^RG5, Gug^RNAi.1.UAS, Scer\GAL4^dpp.blk1 has adult head phenotype

(Wang et al., 2008)

G9a^RG5, Gug^RNAi.1.UAS, Scer\GAL4^dpp.blk1 has melanotic mass phenotype

(Wang et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

37.5% of G9a^RG5 mutant males expressing Gug^{dsRNA.1.Scer\UAS} under the control of Scer\GAL4^dpp.blk1 develop melanotic masses in their heads.

(Wang et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

G9a^RG5

(Marzullo et al., 2023, Seller et al., 2019, Wang et al., 2014)

dG9a^BG5

(Wang et al., 2008)

dG9a^RG5

(Wang et al., 2008, Seum et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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