dG9a, EHMT, EG:BACR37P7.2
histone H3 Lys 9-specific histone methyltransferase - regulator of peripheral dendrite development - larval locomotor behavior - non-associative learning and courtship memory - regulator the expression of insulin-like peptide genes - regulation of starvation-induced autophagy
Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.55
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\G9a using the Feature Mapper tool.
G9a protein is localized in the cytoplasm of spermatocytes in both the growth stage and the onion stage of spermiogenesis. In the elongation stage, G9a signals were mainly found in the cystic bulge. G9a signal was detected in nuclei early in the canoe stage, but disappeared by the end of the canoe stage.
G9a is widely expressed in the nervous system. It is widely abundant in the adult brain but is excluded from neuropilar regions such as the mushroom body calyx. In larval ventral nerve cord, it is expressed in neurons and more weakly in glial cells. It is also detected in multiple dendrite sensory neurons of the PNS in larvae. It is also detected at a low level in non-neuronal tissues including muscle and epidermis.
GBrowse - Visual display of RNA-Seq signalsView Dmel\G9a in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: G9a CG2995
Source for merge of: EG:BACR37P7.2 CG2995
As a gene coding for a protein with a "SET" domain following a bioinformatics search. A BLASTP search against the mouse and human databases revealed the gene to be homologous to the mammalian G9a gene.