FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Eps-15UAS.cKa
Open Close
General Information
Symbol
Dmel\Eps-15UAS.cKa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Koh
FlyBase ID
FBal0219695
Feature type
allele
Associated gene
Dmel\Eps-15
Associated Insertion(s)
Carried in Construct
P{UAS-Eps-15.K}
Key Links
Transgenic product class
cDNA
(Koh et al., 2007)
wild_type
(Koh et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Koh et al., 2007)
wild_type
(Koh et al., 2007)
Mutagen
in vitro construct
(Koh et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Eps-15.K}
Cytology
Description

UASt regulatory sequences drive expression of a full-length Eps-15 cDNA (cDNA clone SD09478).

(Koh et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Eps-15
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Eps-15UAS.cKa, Scer\GAL4elav.Switch.PO is an enhancer of short lived | RU486 conditional phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4elav.Switch.PO

      (Yu et al., 2020)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Eps-15-CR00466-TG4.0/Eps-15UAS.cKa rescues Df(2R)BSC606/Eps-15CR00466-TG4.0

      (Lee et al., 2018)

      Scer\GAL4elav-C155/Eps-15UAS.cKa rescues Eps-15Δ29/Eps-15e75

      (Koh et al., 2007)
      Comments

      Expression of Eps-15Scer\UAS.cKa under the control of either Scer\GAL4elav-C155 or Scer\GAL4elav.PLu rescues the supernumerary bouton phenotype seen at Eps-15Δ29/Eps-15e75 larval neuromuscular junctions. The reduced dye uptake seen at the mutant neuromuscular junctions is also rescued.

      (Koh et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Eps-15Scer\UAS.cKa
      Eps-15UAS.cKa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Koh
      Secondary FlyBase IDs
        References (3)