FlyBase Allele Report: Dmel\Ubx[UAS.cUa]

General Information

Symbol

Dmel\Ubx^UAS.cUa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Unknown

FlyBase ID

FBal0220305

Feature type

allele

Associated gene

Dmel\Ubx

Associated Insertion(s)

Carried in Construct

P{UAS-Ubx.U}

Also Known As

UAS-Ubx

Key Links

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-Ubx.U}

Cytology

Description

UAS regulatory sequences drive expression of Ubx.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Ubx

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | first instar larval stage, with Scer\GAL4^elav-C155

(Estacio-Gómez et al., 2013)

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^ppk.PG

(Parrish et al., 2007)

increased cell number | first instar larval stage, with Scer\GAL4^elav-C155

(Estacio-Gómez et al., 2013)

Phenotype Manifest In

adult somatic muscle cell of thorax, with Scer\GAL4^unspecified

(Bryantsev et al., 2012)

dendrite & dendritic arborising neuron, with Scer\GAL4^ppk.PG

(Parrish et al., 2007)

larval abdominal ganglion Leucokinin neuron | ectopic | first instar larval stage, with Scer\GAL4^elav-C155

(Estacio-Gómez et al., 2013)

larval thoracic neuromere | first instar larval stage, with Scer\GAL4^elav-C155

(Estacio-Gómez et al., 2013)

Detailed Description

Statement

Reference

Flies expressing Ubx^Scer\UAS.cUa in flight muscles under the control of Scer\GAL4^unspecified show a transformation of the large thoracic muscles to non-flight muscle fate, as judged by changes in their myofibril morphology and clustering of their nuclei in a lumen.

(Bryantsev et al., 2012)

Expression of Ubx^Scer\UAS.cUa under the control of Scer\GAL4^ppk.PG results in a reduction in both dendritic branching and total dendritic length in class IV dendrite arborisation (da) neurons in third instar larvae.

Expression of Ubx^Scer\UAS.cUa under the control of Scer\GAL4²²¹ has no effect on the dendrite arborisation patterns of class I da neurons.

(Parrish et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^elav-C155, Ubx^UAS.cUa has abnormal neuroanatomy | first instar larval stage phenotype, non-enhanceable by hth^UAS.GFP/Scer\GAL4^elav-C155

(Estacio-Gómez et al., 2013)