FlyBase Allele Report: Dmel\ham[JF02270]

General Information

Symbol

Dmel\ham^JF02270

Species

D. melanogaster

Name

FlyBase ID

FBal0220660

Feature type

allele

Associated gene

Dmel\ham

Associated Insertion(s)

Carried in Construct

P{TRiP.JF02270}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.3.31)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.3.31)

Mutagen

in vitro construct

(Perkins et al., 2009.3.31)

Progenitor genotype

Carried in construct

P{TRiP.JF02270}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009.3.31)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF02270

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal pain response | third instar larval stage, with Scer\GAL4^ppk.1.9

(Nagy et al., 2015)

abnormal sensory perception | third instar larval stage, with Scer\GAL4^ppk.1.9

(Nagy et al., 2015)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of ham^JF02270 under the control of Scer\GAL4^ppk.1.9 causes hypoalgesia in third instar larvae: the larvae show increased latency response times (decreased nociception) to a noxious thermal stimulus compared to controls.

(Nagy et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, ham^JF02270 is an enhancer of increased cell number | larval stage phenotype of erm^unspecified

(Rives-Quinto et al., 2020)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, ham^JF02270 is an enhancer of type II neuroblast | larval stage | increased number phenotype of erm^unspecified

(Rives-Quinto et al., 2020)

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, ham^JF02270 is an enhancer of larval brain | larval stage phenotype of erm^unspecified

(Rives-Quinto et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

26728

y¹ v¹; P{TRiP.JF02270}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ham^JF02270

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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