FlyBase Allele Report: Dmel\hpo[G3315]

General Information

Symbol

Dmel\hpo^G3315

Species

D. melanogaster

Name

FlyBase ID

FBal0220836

Feature type

allele

Associated gene

Dmel\hpo

Associated Insertion(s)

P{EP}hpo^G3315

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Bellen, 2009.4.8)

Progenitor genotype

Associated Insertion(s)

P{EP}hpo^G3315

Cytology

Description

Insertion in the 5'UTR.

(Genevet et al., 2009)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:19,496,805..19,496,805 [+]

(Jetti et al., 2023, Guo et al., 2020, Sanhueza et al., 2015, Bellen, 2009.4.8, Genevet et al., 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates amyotrophic lateral sclerosis type 8

modeled by Vap33^{P58S.UAS.Tag:FLAG}

(Sanhueza et al., 2015)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | third instar larval stage, with Scer\GAL4^nub.PU

(Guo et al., 2020)

Phenotype Manifest In

wing pouch | third instar larval stage, with Scer\GAL4^nub.PU

(Guo et al., 2020)

Detailed Description

Statement

Reference

Expressing hpo^G3315 under the control of Scer\GAL4^nub.PU induces a small third instar wing pouch.

(Guo et al., 2020)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^nub.PU, hpo^G3315 has decreased size | third instar larval stage phenotype, suppressible | partially by Rox8^GD11645, Scer\GAL4^nub.PU

(Guo et al., 2020)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^nub.PU, hpo^G3315 has wing pouch | third instar larval stage phenotype, suppressible | partially by Rox8^GD11645, Scer\GAL4^nub.PU

(Guo et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

27105

y¹ w^*; P{EP}hpo^G3315

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

hpo^G3315

(Bellen, 2009.4.8)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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