FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Atg310
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General Information
Symbol
Dmel\Atg310
Species
D. melanogaster
Name
FlyBase ID
FBal0221317
Feature type
allele
Associated gene
Dmel\Atg3
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Scott et al., 2007)
Progenitor genotype
P{EPgy2}Atg3EY08396
(Scott et al., 2007)
Caused by aberration
Df(3L)Aut110
Cytology
Description

Imprecise excision of the P{EPgy2}Aut1EY08396 insertion, resulting in a deletion that eliminates 838bp upstream of the original insertion site, which includes the first and part of the second exon of the neighbouring Nufip gene, as well as Aut1 5' UTR sequences.

(Scott et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Starvation-induced autophagy is significantly reduced compared to wild type in Aut110/Df(3L)Cat animals.

      (Scott et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Atg310/Atg310 is a suppressor of increased cell death phenotype of Atg1UAS.cSa, Scer\GAL4Cg.PA

      (Scott et al., 2007)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The induction of autophagy caused by expression of Atg1Scer\UAS.cSa under the control of Scer\GAL4hs.PH is suppressed by Aut110/Df(3L)Cat.

      (Scott et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Atg310
      (Billes et al., 2018, Chang et al., 2013, Scott et al., 2007)
      Atg3[10]
      (Nagy et al., 2015)
      Aut110
      (Scott et al., 2007)
      atg310
      (Valko et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)