FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mmp1Q273
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General Information
Symbol
Dmel\Mmp1Q273
Species
D. melanogaster
Name
FlyBase ID
FBal0221514
Feature type
allele
Associated gene
Dmel\Mmp1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        ameliorates  carcinoma
        modeled by Ras85DV12.UAS, scrib1
        (Srivastava et al., 2007)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        53.7% of Mmp1Q273 pupae show wing eversion defects 6 hours after puparium formation (eversion is complete at this time in wild-type animals); 38.9% have partially everted wings and 14.8% show a complete failure of disc eversion. 22.2% have leg eversion defects.

        The basement membrane of wing discs is not degraded in Mmp1Q273 pupae which fail to evert their wing discs.

        (Srivastava et al., 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressor of
        Phenotype Manifest In
        Suppressor of
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The invasive behaviour of clones in the eye antennal disc which are expressing Ras85DV12.Scer\UAS under the control of Scer\GAL4Act5C and are also homozygous for scrib1 is partially suppressed in a Mmp1Q273 homozygous background.

        (Srivastava et al., 2007)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Mmp1Q273
        (Srivastava et al., 2007)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)