FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\heixNP5301
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General Information
Symbol
Dmel\heixNP5301
Species
D. melanogaster
Name
FlyBase ID
FBal0222350
Feature type
allele
Associated gene
Dmel\heix
Associated Insertion(s)
P{GawB}heixNP5301
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}heixNP5301
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        exacerbates  Parkinson's disease
        modeled by Pink1B9
        (Vos et al., 2012)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Feeding hemizygous animals with the MK-4 form of vitamin K[[2]], but not with menadione (a synthetic precursor that is prenylated to form vitamin K[[2]]) or with ubiquinone significantly improves their survival rate.

        (Vos et al., 2012)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        heix[+]/heixNP5301 is an enhancer of abnormal flight phenotype of Pink1B9

        (Vos et al., 2012)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        NP5301
        (Vos et al., 2012)
        heixNP5301
        Name Synonyms
        Secondary FlyBase IDs
          References (2)