FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Su(H)VP16.UAS.cSa
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General Information
Symbol
Dmel\Su(H)VP16.UAS.cSa
Species
D. melanogaster
Name
FlyBase ID
FBal0230375
Feature type
allele
Associated gene
Dmel\Su(H)
Associated Insertion(s)
Carried in Construct
P{UAS-Su(H).VP16.S}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Vied and Kalderon, 2009)
Progenitor genotype
Carried in construct
P{UAS-Su(H).VP16.S}
Cytology
Description

UAS regulatory sequences drive expression of Su(H) which is fused to the VP16 activation domain.

(Vied and Kalderon, 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Su(H)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Follicle stem cell clones expressing Su(H)Scer\UAS.cSa.T:Hsim\VP16 under the control of Scer\GAL4tub, Scer\GAL4Act and Scer\GAL4e22c simultaneously are lost more rapidly from the ovarioles than control clones over time.

      Follicle stem cell clones expressing Su(H)Scer\UAS.cSa.T:Hsim\VP16 under the control of Scer\GAL4tub are lost more rapidly from the ovarioles than control clones over time.

      (Vied and Kalderon, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Su(H)VP16.UAS.cSa/Scer\GAL4Tub.PU is a non-suppressor of follicle stem cell | somatic clone phenotype of mam8

      (Vied and Kalderon, 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Su(H)Scer\UAS.cSa.T:Hsim\VP16 under the control of Scer\GAL4tub has no effect on the maintenance of mam8 follicle stem cell clones.

      The ability of ptcS2 to induce follicle stem cell duplications in clones and for the clones to take over the whole ovariole is suppressed by expression of Su(H)Scer\UAS.cSa.T:Hsim\VP16 under the control of Scer\GAL4tub. The loss of follicle stem cell clones caused by expression of Su(H)Scer\UAS.cSa.T:Hsim\VP16 under the control of Scer\GAL4tub is not substantially suppressed by ptcS2.

      (Vied and Kalderon, 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Su(H)Scer\UAS.cSa.T:Hsim\VP16
      Su(H)VP16.UAS.cSa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)