FB2026_03 , released September 17, 2026
Allele: Dmel\sns5xPDZ.UAS.Tag:HA
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General Information
Symbol
Dmel\sns5xPDZ.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0230381
Feature type
allele
Associated gene
Dmel\sns
Associated Insertion(s)
Carried in Construct
P{UAS-sns.5xPDZ-HA}
Key Links
Transgenic product class
missense_variant
(Kocherlakota et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Kocherlakota et al., 2008)
Mutagen
in vitro construct
(Kocherlakota et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-sns.5xPDZ-HA}
Cytology
Description

UASt regulatory sequences drive expression of sns, in which all 5 potential PDZ-domain binding motifs have been mutated (amino acid replacements D1135N, V1137G, E1140Q, L1142G, S1143A, V1145G, T1173A, L1175G, V1176G, E1177Q, L1481G and V1482G). The coding sequence is tagged at the C-terminal end with a single Tag:HA tag.

(Kocherlakota et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
sns
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      sns5xPDZ.UAS.Tag:HA/Scer\GAL4sns.PK rescues snsZF1.4

      (Kocherlakota et al., 2008)

      Scer\GAL4Mef2.PR/sns5xPDZ.UAS.Tag:HA rescues snsXB3/snsZF1.4

      (Kocherlakota et al., 2008)
      Comments

      The myoblast fusion defects of snsXB3/snsZF1.4 embryos are rescued by expression of sns5xPDZ.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Mef2.PR.

      The myoblast fusion defects of snsZF1.4/snsZF1.4 embryos are rescued by expression of sns5xPDZ.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4sns.PK.

      (Kocherlakota et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sns5xPDZ.Scer\UAS.T:Ivir\HA1
      sns5xPDZ.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)