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General Information
Symbol
Dmel\Vps20I3
Species
D. melanogaster
Name
FlyBase ID
FBal0230477
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

A22608854T

Comment:

AG to TG mutation in the splice acceptor before the third coding exon.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Vps20I3 contains a splice acceptor mutation leading to a truncation, removing 151 residues from the C-terminus.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous Vps20I3 mutant tissue partially survives in mosaic eye discs, and is not completely 'out-competed'. Although mutant ommatidia are not recovered, the wild-type ommatidia composing the adult eyes of mosaic animals are variably overgrown.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Other
Phenotype Manifest In
Suppressor of
Statement
Reference

Vps20I3 is a suppressor of wing vein L5 phenotype of rhove-1

Vps20I3 is a suppressor of wing vein L5 phenotype of Df(3L)ru-22/rhove-1

Additional Comments
Genetic Interactions
Statement
Reference

A Vps20I3 heterozygous background leads to approximately 90% suppression of the L5 wing vein defect in rhove-1/Df(3L)ru-22 kst1 flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)