FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CCT8KK100186
Open Close
General Information
Symbol
Dmel\CCT8KK100186
Species
D. melanogaster
Name
FlyBase ID
FBal0230611
Feature type
allele
Associated gene
Dmel\CCT8
Associated Insertion(s)
Carried in Construct
P{KK100186}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK100186}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK100186
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing CCT8KK100186 under the control of Scer\GAL4ey.PU results in complete loss of head structures in pharate adults.

      Expressing CCT8KK100186 under the control of Scer\GAL4GMR.PU fails to induce cell death in the posterior compartment of the eye disc in third instar larvae, and results in adults with normal eyes.

      (Kim and Choi, 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      NOT Enhancer of
      NOT Suppressor of
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      CCT8KK100186, Scer\GAL4GMR.PU is an enhancer of eye phenotype of Scer\GAL4GMR.PU, Zzzz\GGGGCC36.UAS

      (Ortega et al., 2020)
      NOT Enhancer of
      Statement
      Reference

      CCT8KK100186, Scer\GAL4GMR.PU is a non-enhancer of eye phenotype of Scer\GAL4GMR.PU, Zzzz\GGGGCC30.UAS.EGFP

      (Ortega et al., 2020)
      NOT Suppressor of
      Statement
      Reference

      CCT8KK100186, Scer\GAL4GMR.PU is a non-suppressor of eye phenotype of Scer\GAL4GMR.PU, Zzzz\GGGGCC30.UAS.EGFP

      (Ortega et al., 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CCT8KK100186
      CG8258KK100186
      Name Synonyms
      Secondary FlyBase IDs
        References (6)