FlyBase Allele Report: Dmel\CSN6[KK100377]

General Information

Symbol

Dmel\CSN6^KK100377

Species

D. melanogaster

Name

FlyBase ID

FBal0230708

Feature type

allele

Associated gene

Dmel\CSN6

Associated Insertion(s)

Carried in Construct

P{KK100377}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK100377}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK100377

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage, with Scer\GAL4^elav.PU

(Tsou et al., 2012)

lethal - all die before end of pupal stage, with Scer\GAL4^sqh.PW

(Tsou et al., 2012)

short lived, with Scer\GAL4^elav.PU

(Tsou et al., 2012)

some die during pupal stage, with Scer\GAL4^sqh.PW

(Tsou et al., 2012)

visible, with Scer\GAL4^dpp.PU

(Zhang et al., 2012)

Phenotype Manifest In

scutellar bristle, with Scer\GAL4^dpp.PU

(Zhang et al., 2012)

trichogen cell, with Scer\GAL4^dpp.PU

(Zhang et al., 2012)

Detailed Description

Statement

Reference

Most Scer\GAL4^elav.PU, CSN6^KK100377 die soon after eclosing. Surviving adults are slower than controls and die by 20 days.

(Tsou et al., 2012)

Expression of CSN6^KK100377 under the control of Scer\GAL4^bbg-C96 does not result in a wing phenotype.

Expression of CSN6^KK100377 under the control of Scer\GAL4^dpp.PU results in stunted scutellar bristles and a phenotype of two bristle shafts in one socket is seen.

(Zhang et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

CSN6^KK100377, Scer\GAL4^unspecified, ninaE^P37H.GMR has visible | adult stage phenotype

(Park et al., 2023)

CSN6^KK100377, Scer\GAL4^unspecified, ninaE^P37H.GMR has decreased size | adult stage phenotype

(Park et al., 2023)

Phenotype Manifest In

Other

Statement

Reference

CSN6^KK100377, Scer\GAL4^unspecified, ninaE^P37H.GMR has eye phenotype

(Park et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v105385

P{KK100377}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

CSN6^KK100377

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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