FlyBase Allele Report: Dmel\Scsα1[KK102542]

General Information

Symbol

Dmel\Scsα1^KK102542

Species

D. melanogaster

Name

FlyBase ID

FBal0231850

Feature type

allele

Associated gene

Dmel\Scsα1

Associated Insertion(s)

Carried in Construct

P{KK102542}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK102542}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK102542

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates brain cancer

modeled by brat^KK113206

(Rebelo and Homem, 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | adult stage, with Scer\GAL4^ey.PU

(Choo et al., 2015)

lethal, with Scer\GAL4^αTub84B.PL

(François et al., 2023)

male fertile, with Scer\GAL4^nanos.PG

(François et al., 2023)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PU

(Choo et al., 2015)

indirect flight muscle | adult stage, with Scer\GAL4^Act88F.PB

(González Morales et al., 2023)

myofibril | adult stage, with Scer\GAL4^Act88F.PB

(González Morales et al., 2023)

Detailed Description

Statement

Reference

The expression of Scsα1^KK102542 under the control of Scer\GAL4^ey.PU induces the loss of cells at the posterior end of the eye.

(Choo et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Scsα1^KK102542/Scer\GAL4^ey.PU is a non-enhancer of eye phenotype of Scer\GAL4^ey.PU, sesB^KK108773

(Choo et al., 2015)

Scsα1^KK102542, Scer\GAL4^ey.PU is a non-enhancer of eye phenotype of Men-b^GL00415, Scer\GAL4^ey.PU

(Choo et al., 2015)

Scsα1^KK102542, Scer\GAL4^ey.PU is a non-enhancer of eye phenotype of Fum1^KK108008, Scer\GAL4^ey.PU

(Choo et al., 2015)

NOT Suppressor of

Statement

Reference

Scsα1^KK102542/Scer\GAL4^ey.PU is a non-suppressor of eye phenotype of Scer\GAL4^ey.PU, sesB^KK108773

(Choo et al., 2015)

Scsα1^KK102542, Scer\GAL4^ey.PU is a non-suppressor of eye phenotype of Men-b^GL00415, Scer\GAL4^ey.PU

(Choo et al., 2015)

Scsα1^KK102542, Scer\GAL4^ey.PU is a non-suppressor of eye phenotype of Fum1^KK108008, Scer\GAL4^ey.PU

(Choo et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v107164

P{KK102542}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Scs-α^RNAi

(Bonnay et al., 2020)

Scsα1^KK102542

Scsα^KK102542

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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