FlyBase Allele Report: Dmel\Su(z)2[KK103634]

General Information

Symbol

Dmel\Su(z)2^KK103634

Species

D. melanogaster

Name

FlyBase ID

FBal0232433

Feature type

allele

Associated gene

Dmel\Su(z)2

Associated Insertion(s)

Carried in Construct

P{KK103634}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK103634}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK103634

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates cancer

modeled by dlg1², dlg1^A40.2

(Bunker et al., 2015)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^en-e16E/Su(z)2^KK103634 is an enhancer of neoplasia | third instar larval stage phenotype of dlg1²

(Bunker et al., 2015)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^en-e16E/Su(z)2^KK103634 is an enhancer of wing disc | third instar larval stage phenotype of dlg1²

(Bunker et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

The expression of Su(z)2^KK103634 under the control of Scer\GAL4^en-e16E enhances the tumor phenotype of dlg1²/dlg1^A40.2 transheterozygous third instar larval wing discs, as it leads to a significantly increased cell number in the discs' posterior compartment.

(Bunker et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v100096

P{KK103634}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Su(z)2^KK103634

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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