FlyBase Allele Report: Dmel\exd[KK107300]

General Information

Symbol

Dmel\exd^KK107300

Species

D. melanogaster

Name

FlyBase ID

FBal0234853

Feature type

allele

Associated gene

Dmel\exd

Associated Insertion(s)

Carried in Construct

P{KK107300}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK107300}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK107300

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates acute myeloid leukemia

modeled by Hsap\HOXA9::Hsap\NUP98^WT.UAS

(Gavory et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

The expression of exd^KK107300 under the control of Scer\GAL4^c564 has no obvious affect on the inflammatory response to Gram-positive bacterial infection or under basal conditions, as compared to controls.

(Kumar et al., 2016)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

exd^KK107300, Scer\GAL4^ey.PH is a suppressor of visible | adult stage phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^ey.PH

(Gavory et al., 2021)

exd^KK107300, Scer\GAL4^ey.PH is a suppressor of abnormal size | adult stage phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^ey.PH

(Gavory et al., 2021)

exd^KK107300, Scer\GAL4^Act5C.PP is a suppressor of neoplasia | adult stage | somatic clone - tissue specific phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Act5C.PP, hth^UAS.GFP

(Gavory et al., 2021)

Scer\GAL4^Act5C.PP/exd^KK107300 is a suppressor of decreased size | adult stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PP, hth^UAS.GFP

(Gavory et al., 2021)

Phenotype Manifest In

Suppressor of

Statement

Reference

exd^KK107300, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^ey.PH

(Gavory et al., 2021)

exd^KK107300, Scer\GAL4^Act5C.PP is a suppressor of adult cuticle | somatic clone - tissue specific phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Act5C.PP, hth^UAS.GFP

(Gavory et al., 2021)

exd^KK107300, Scer\GAL4^Act5C.PP is a suppressor of adult head | somatic clone - tissue specific phenotype of Hsap\HOXA9::Hsap\NUP98^WT.UAS, Scer\GAL4^Act5C.PP, hth^UAS.GFP

(Gavory et al., 2021)

Scer\GAL4^Act5C.PP/exd^KK107300 is a suppressor of eye | adult stage | somatic clone - tissue specific phenotype of Scer\GAL4^Act5C.PP, hth^UAS.GFP

(Gavory et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v100259

P{KK107300}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

exd^KK107300

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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