FlyBase Allele Report: Dmel\Ndfip[KK108770]

General Information

Symbol

Dmel\Ndfip^KK108770

Species

D. melanogaster

Name

FlyBase ID

FBal0235803

Feature type

allele

Associated gene

Dmel\Ndfip

Associated Insertion(s)

Carried in Construct

P{KK108770}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK108770}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK108770

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

wing vein, with Scer\GAL4^Bx-MS1096

(Dalton et al., 2011)

Detailed Description

Statement

Reference

Knockdown of Ndfip in the wing via Scer\GAL4^Bx-MS1096-mediated expression of Ndfip^KK108770 (in the presence of P{UAS-Dcr-2.D}) results in minor vein defects.

(Dalton et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL80^ts.αTub84B, Ndfip^KK108770, Scer\GAL4^da.PU is a suppressor | heat sensitive of lethal - all die during pupal stage | heat sensitive phenotype of Scer\GAL4^da.PU, Scer\GAL80^ts.αTub84B, fzr^RNAi.UAS.WIZ

(Neuert et al., 2017)

Phenotype Manifest In

Enhancer of

Statement

Reference

Ndfip^KK108770/Scer\GAL4^Bx-MS1096 is an enhancer of wing margin phenotype of N^264-39

(Dalton et al., 2011)

Ndfip^KK108770/Scer\GAL4^Bx-MS1096 is an enhancer of wing vein phenotype of N^264-39

(Dalton et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Scer\GAL4^Bx-MS1096-mediated expression of Ndfip^KK108770 enhances the wing margin notching and slight vein thickening near the wing blade seen in N^264-39/+ wings.

(Dalton et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v104434

P{KK108770}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG32177^KK108770

Ndfip^KK108770

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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